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Table 2 Treatment importance of the top AML proteins in the context of the candidates

From: Learning the therapeutic targets of acute myeloid leukemia through multiscale human interactome network and community analysis

AML proteins

Fostamatinib

Lasofoxifene

Zinc

L-Glutamic acid

MYC

8

6

5

2

RUNX3

102

97

237

276

STAT3

11

9

34

32

IDH1

336

280

256

6

ANXA2

23

15

21

30

GATA1

41

16

63

56

NPM1

16

10

15

12

SPI1

134

38

132

139

PSIP1

183

41

156

164

GATA2

54

33

80

68

KRAS

13

17

20

5

NSD1

105

32

200

218

GFI1

182

80

190

153

HSPB1

17

19

32

11

EHMT2

136

28

124

123

RUNX1

62

52

42

67

  1. The treatment importance values of the top acute myeloid leukemia proteins are shown in the table according to the respective top 4 candidates. The bolded numbers have a treatment importance rank that is one to 50
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BioData Mining

ISSN: 1756-0381