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Table 3 List of SNPs significantly associated with the SPARE-AD index. rsID is a unique identifier for a specific SNP. CHR refers to the chromosome on which the SNP is located, and BP stands for the base pair position of the SNP on the chromosome. REF represents the reference allele, and EA stands for effect allele. P-value indicates the statistical significance of the association between the SNP and the SPARE-AD index. Gene is the name of the gene in which the SNP is located

From: High-dimensional mediation analysis reveals the mediating role of physical activity patterns in genetic pathways leading to AD-like brain atrophy

rsID

CHR: BP

REF/EA

P-value

Gene

rs75589364

chr6:33373881

A/G

1.33E-08

KIFC1

rs75086869

chr6:33397796

G/A

3.34E-08

OMIM

rs11042786

chr11:10432928

G/C

4.28E-08

AMPD3

rs67457110

chr11:10433888

C/T

4.75E-08

AMPD3

rs1376001

chr11:10452442

C/T

1.31E-09

AMPD3

rs11605232

chr11:10468501

T/C

4.33E-08

AMPD3

rs11604780

chr11:10468671

A/G

4.79E-08

AMPD3

rs11604833

chr11:10468906

A/G

3.82E-08

AMPD3

rs11604838

chr11:10468953

A/G

4.19E-08

AMPD3

rs7938316

chr11:10472064

C/T

4.87E-08

AMPD3

rs7949917

chr11:10475370

G/A

3.16E-10

AMPD3

rs7950039

chr11:10475467

G/A

3.28E-10

AMPD3

rs4909930

chr11:10475761

G/A

3.32E-10

AMPD3

rs4909931

chr11:10475772

G/T

3.65E-10

AMPD3

rs4909932

chr11:10475967

A/G

4.39E-10

AMPD3

rs899013

chr11:10476689

A/G

4.62E-10

AMPD3

rs7130140

chr11:10489826

A/C

1.77E-09

AMPD3

NA

chr11:10498470

T/TAGCA

3.71E-10

AMPD3

rs4910143

chr11:10499103

A/G

2.26E-10

AMPD3

rs4910144

chr11:10501304

C/G

4.16E-10

AMPD3

rs10840425

chr11:10504640

A/C

1.75E-09

AMPD3

rs10770119

chr11:10506255

G/T

5.05E-09

AMPD3